R:GEN® AND CORE TECHNOLOGY

R:GEN and Core Technology

R:GEN®

Innovative Laser Solution for Common Retinal Diseases

Selective Retina Therapy
527 nm wavelength & 1.7 µs pulse duration
Ramping Technology
Real Time Feedback Technology

RTF Sensor (Disposable)

The RTF sensor enables selective retinal treatment by detecting the pressure wave of microbubble generated after irradiation with R:GEN® laser.

Ideal Wavelength and Pulse Duration (527 nm / 1.7 μs)

The R:GEN® with 527 nm wavelength and 1.7 μs pulse width is ideal for selectively damaging RPE cells while sparing other retinal tissues.

Ref. JOURNAL OF THE OPTICAL SOCIETY OF AMERICA, VOL. 60, NO. 2

Bull. Soc. Belge Ophtalmol 302 (2006): 51-69.

Ramping Technology

Rapidly produce 15 laser pulses with ramping up energies to check the optimal pulses for patient.

Ref. Kim MK, et al. Graefes Arch Clin Exp Ophthalmol. 2018 Sep;256(9):1639-1651; High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics [Internet]. Cham (CH): Springer; 2019. Chapter 11.

Real-time Feedback Technology

R:GEN® utilizes optoacoustic and reflectometry to ensure the appropriate treatment energy. Real-Time Feedback technology detects sound wave & back scattering light from RPE microbubbles generated by laser and irradiation automatically stops when microbubble formation is detected.

R:GEN MOA

R:GEN® MECHANISM OF ACTION

How R:GEN® works

When problematic RPE cells are treated by R:GEN®, the irradiated RPE cells are destroyed without damaging
neighbor photoreceptors. Subsequently, RPE cell regeneration is induced which results in improvement of the retinal metabolism.